Cilia-based Transport Networks in the Brain and Synthetic Biology

Title:Cilia-based Transport Networks in the Brain and Synthetic Biology  

Reporter:Prof. Eberhard Bodenschatz

Time:14:00-16:00am, Nov. 25, 2016(Friday) 

Place:Lecture Hall, Department of Thermal Engineering  

Abstract:Cerebrospinal fluid conveys many physiologically important signaling factors through the ventricular cavities of the brain. We investigated the transport of cerebrospinal fluid in the third ventricle of the mouse brain and discovered a highly organized pattern of cilia modules, which collectively  give rise to a network of fluid flows that allows for precise transport within this ventricle. Our work suggests that ciliated epithelia can generate and maintain complex, spatiotemporally regulated flow networks. I shall also show results on how to assemble artificial cilia and cilia carpets.

Brief Biography:He received his doctorate in theoretical physics from the University of Bayreuth in 1989. In 1991, during his postdoctoral research at the University of California at Santa Barbara, he received a faculty position in experimental physics at Cornell University. From 1992 until 2005, during his tenure at Cornell he was a visiting professor at the University of California at San Diego (1999-2000). In 2003 he became a Scientific Member of the Max Planck Society and an Adjunct Director (2003-2005)/ Director (since 2005) at the Max Planck Institute for Dynamics and Self-Organization. He continues to have close ties to Cornell University, where he is Adjunct Professor of Physics and of Mechanical and Aerospace Engineering (since 2005).