Prof. Dr. Meixiang WANG

Tel: 86-10-62796761



Prof. Dr. Wang received a BS degree in 1983 from the Department of Chemistry, Fudan University. After spending 3 years in General Research Institute of Non-ferrous Metals as a research associate, he joined Institute of Chemistry, Chinese Academy of Sciences (ICCAS) at Beijing as a research student. He obtained his master degree (1989) and PhD (1992) under the supervision of Professor Zhi-Tang Huang. He then worked at ICCAS in the next 17 years, ranking from assistant professor, associate professor and professor. During 2000 to 2004, he served as the Director of ICCAS. Since the May of 2009, he has become a professor of chemistry in Tsinghua University. His research interests include enantioselective biotransformations using whole cell catalysts, selective organic reactions for the synthesis of natural products and bioactive compounds, and supramolecular chemistry of novel heteroatom-bridged calixaromatics.


Acdamic Memberships

Org. Chem. Front. (associate editor)

International Conference on Calixarene (advisory committee member)

Asian J. Org. Chem. (international advisory board member);

Beilstein J. Org. Chem. (advisory board member)

Supramol. Chem. (editorial board member)

Chinese J. Chem. (executive editorial board member)



中国科学 – 化学 (编委)



Research interests



Selected recent publications

1.      Zhi-Chen Wu, Qing-Hui Guo, Mei-Xiang Wang,* “Corona[5]arenes Accessed by a Macrocycle-to-Macrocycle Transfromation and a One-pot Three-Component Reaction”, Angew Chem. Int. Ed. 2017, 56, DOI: 10.1002/anie.201703008.

2.      Xin-Ming Xu, Liang Zhao, Jieping Zhu, Mei-Xiang Wang,* “Catalytic Asymmetric Tandem Reaction of Tertiary Enamides: Expeditious Synthesis of Pyrrolo[2,1-a]isoquinoline Alkaloid Derivatives”, Angew Chem. Int. Ed. 2016, 55, 3799-3803.

3.      Yun Zhang, Yu-Fei Ao, Zhi-Tang Huang, De-Xian Wang,* Mei-Xiang Wang,* Jieping Zhu,* “Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct”, Angew Chem. Int. Ed. 2016, 55, 5282-5285.

4.      Qing-Hui Guo, Liang Zhao, Mei-Xiang Wang,* “Synthesis and molecular recognition of water-soluble S6-corona[3]arene[3]pyridazines”, Angew Chem. Int. Ed. 2015, 54, 8386-8389.

5.      Mei-Xiang Wang,* “Enantioselective biotransformations of nitriles in organic synthesis”, Acc. Chem. Rev. 2015, 48, 602-611.

6.      Mei-Xiang Wang,* “Exploring tertiary enamides as versatile synthons in organic synthesis”, Chem. Commun. 2015, 51, 6039-6049 (an invited feature article).

7.      Qing-Hui, Guo, Zhan-Da Fu, Liang Zhao, Mei-Xiang Wang,* “Synthesis, structure, and properties of O6-corona[3]arene[3]tetrazines”, Angew. Chem. Int. Ed. 2014, 53, 13548-13552.

8.      Hu, Zhang, Bo Yao, Liang Zhao, De-Xian Wang, Bo-Xing Xu, Mei-Xiang Wang,* “Direct synthesis of high-valent aryl-Cu(II) and aryl-Cu(III) compounds: mechanistic insight into arene C-H bond metalation”, J. Am. Chem. Soc. 2014, 136, 6326-6332.

9.      Chuan-Hu Lei, De-Xian Wang, Liang Zhao, Jieping Zhu, Mei-Xiang Wang,* “Synthesis of substituted pyridines from cascade [1+5] cycloaddition of isonitriles to N-formylmethyl-substituted enamides, aerobic oxidative aromatization, and acyl transfer reaction”, J. Am. Chem. Soc. 2013, 135, 4708-4711.

10.  De-Xian Wang,* Mei-Xiang Wang,* “Anion-p interactions: generality, binding strength and structure”, J. Am. Chem. Soc. 2013, 135, 892-897.

11.  Mei-Xiang Wang,* “Nitrogen and oxygen bridged calixaromatics: synthesis, structure, functionalization, and molecular recognition”, Acc. Chem. Res. 2012, 45, 182-195.

12.  Cai-Yan Gao, Liang Zhao,* Mei-Xiang Wang,* “Stabilization of a reactive polynuclear silver carbide cluster through the encapsulation within a supramolecular cage”, J. Am. Chem. Soc. 2012, 134, 824-827.

13.  Shuo Tong, De-Xian Wang, Liang Zhao, Jieping Zhu, Mei-Xiang Wang*, “Enantioselective synthesis of 4-hydroxytetrahydropyridine derivatives by intramolecular addition of tertiary enamides to aldehydes”, Angew. Chem. Int. Ed. 2012, 124, 4493-4496.

14.   Placido Neri, Jonathan Sessler, Mei-Xiang Wang (Eds.) “Calixarenes and Beyond”, Springer, 2016.

15.   Jieping Zhu, Qian Wang, Mei-Xiang Wang (Eds.), “Multicomponent Reactions in Organic Synthesis”, Wiley-VCH, Weinheim, 2014.

16.  《化学生物学进展》张礼和,王梅祥(主编),化学工业出版社,2005年

17.  《有机化学-结构与功能》K. Peter C. Vollhardt, Neil E. Schore原著第四版,戴立信,席振锋,王梅祥(翻译),化学工业出版社,2006年

18.  《手性合成与手性药物》林国强,王梅祥(主编),杜灿屏,吴镭(副主编),化学工业出版社,2008年