Jin GU,  Ph.D.
Associate Professor
Department of Automation
MOE Key Laboratory of Bioinformatics / BRINST Bioinformatics Division
Tel: +86 (10) 6279 4294 ext 866       Email: jgu@tsinghua.edu.cn

Education background

Ph. D. in Control Science and Engineering, Tsinghua University, Beijing, China, 2009
B.S. in Automation, Tsinghua University, Beijing, China, 2004


Lecturer, Tsinghua University, Jul. 2009 – Dec. 2015
Assistant Professor, Tsinghua University, Jan. 2015 – Dec. 2017
Associate Professor, Tsinghua University, Dec. 2017 –

Areas of Research Interests/ Research Projects

Multiple-layer and network-based association study on microRNAs and cell phenotypes, PI, supported by NSFC, 2011.01-2013.12

Research Status

Artificial intelligence for precision oncology
Single cell bioinformatics
Biological networks modeling and analysis
Tools and databases for large-scale cancer omics data

Personal homepage:

Academic Achievement

Databases and Tools:
[1] ClustEx: responsive gene module identification package (v0.3)

[2] PCS: de novo k-mer analysis package (v1.5)

[3] Mamm miR-EST: the ESTs mapped to the flanking sequences of miRNAs

Journal Publications:
[1] Jin Gu, Yang Chen, Shao Li, Yanda Li. Identification of responsive gene modules by network-based gene clustering and extending: application to inflammation and angiogenesis. BMC Systems Biology 2010, 4:47.

[2] Jin Gu. Brief review: frontiers in the computational studies of gene regulations. Frontier of Electrical Electronic Engineering in China 2008, 3(3):251-259.

[3] Xiaowo Wang, Jin Gu, Michael Zhang, Yanda Li. Identification of phylogenetically conserved microRNA cis-regulatory elements across 12 Drosophila species. Bioinformatics 2008, 24(2):165-171.

[4] Tao He, Fei Li, Jin Gu, Ruiqiang Li, Fei Li. Computational Identification of 99 Invertebrate MicroRNAs with Comparative Genomics. Tsinghua Science and Technology 2008, 13(4):425-432.

[5] Jin Gu, Hu Fu, Xuegong Zhang, Yanda Li. Identifications of conserved 7-mers in 3'-UTRs and microRNAs in Drosophila. BMC Bioinformatics 2007, 8:32.

[6] Jin Gu, Tao He, Yunfei Pei, Fei Li, Jing Zhang, Xiaowo Wang, Xuegong Zhang, Yanda Li. Primary Transcripts and Expressions of Mammal Intergenic MicroRNAs Detected by Mapping ESTs to Their Flanking Sequences. Mammalian Genome 2006, 17(10):1033-1041.

[7] Xiaowo Wang, Jing Zhang, Fei Li, Jin Gu, Tao He, Xuegong Zhang, Yanda Li. MicroRNA Identification Based on Sequence and Structure Alignment. Bioinformatics 2005, 21(18):3610-3614.

Conference Publications:
[1] Dingming Wu, Michael Q Zhang, Jin Gu. A new gene network clustering algorithm based on minimum spanning tree. The 4th Chinese National Bioinformatics and Systems Biology Conference, 2010, Hangzhou. (Poster)

[2] Ting Wang, Jin Gu, Rui Li, Shiwen Zhao, Yanda Li. Defining gene expression adaptive responses regulated by microRNAs and transcription factors in human umbilical vein endothelial cells. Computational Biology 2010, Suzhou Dushu Lake Conference Center. (Abstract & Oral Presentation)

[3] Jin Gu. A multiple-instance scoring method to predict tissue-specific cis-regulatory motifs and regions. The International MultiConference of Engineers and Computer Scientists (IMECS'10) 2010, Vol I:186-190. (Oral Presentation)

[4] Jin Gu, Shao Li, Yang Chen, Yanda Li. Integrative computational identifications of the signaling pathway network related to TNF-alpha stimulus in vascular endothelial cells. International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing (IJCBS'09) 2009, 422-427. (Oral Presentation)