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姓  名:陆  韻
所在单位:环境生物学教研所
职  称:副教授
办公电话:(86)-10-62796255
电子邮件:luyun@tsinghua.edu.cn
办公地点:北京海淀区清华大学环境节能楼724,100084


教育背景

1995.9-1999.7     清华大学生物科学与技术系 理学学士

1999.9-2005.1     清华大学生物科学与技术系 生物学博士

工作履历

2005.4-2009.7    美国杜克大学细胞生物学系 博士后(research associate)

2009.12-             清华大学环境学院 副教授   

2017.1-               清华大学环境环境学院 特聘研究员                                       

学术兼职

中国环境科学学会环境医学与健康分会会员

中国毒理学会环境与生态毒理专业委员会会员

研究领域

从毒理学的角度研究环境污染物与人类健康之间的关系。包括以基因组技术为基础的新的毒性检测和预测方法研究,以分子生物学和细胞生物学为基础的毒性机理研究,新兴有毒污染物的筛选,污染物健康基准和标准的研究等。

研究概况

实验室致力于解决三大问题:什么污染物是对健康有害的?这些污染物为什么有害?环境中多大量的污染物才对健康有害?主持和参与的项目有:

1. 国家科技重大专项项目《水体污染控制与治理科技重大专项》下子课题《再生水亲水景观微量靶污染物检测与防控技术体系》,2017ZX07103-004,2017.1-2020.6,主要参与人,负责部分137.28万。

2. 国家自然科学基金面上项目《城市杂用再生水吸入暴露风险因子研究》,No. 21777084,2018.1-2021.12,65万,项目负责人。

3. 国家重点研发计划项目,政府间国际科技创新合作重点专项《再生水安全供水系统与关键技术》,2016YFE0118800,2016.12-2019.12,1675万,主要参与人,负责部分110万。

4. 国家重点研发计划项目《京津冀水资源安全保障技术研发集成与示范应用》下课题《京津冀非常规水安全利用技术研发示范》,2016YFC0401405,2016.7-2020.12,负责部分55万,主要参与人。

5. 国家自然科学基金面上项目《再生水中新兴雌激素活性消毒副产物的亲和分离鉴定及其生成规律的研究》,NO. 21377066, 2014.1-2017.12,82万,项目负责人。

6. 国家高技术研究发展计划(863计划)《再生水的安全性评价与控制技术》,NO. 2013AA065205, 2013.1-2015.12,负责部分60万,主要参与人。

7. 清华大学自主科研青年教师自主选题基础研究项目,《基于雌激素受体致病机理的污染物筛选与鉴定》,2011.7-2014.6,62万,项目负责人。

8. 环保部水专项(与中国环境科学研究院合作),《重点流域优控污染物水环境质量基准研究》,2012.1-2015.12,负责部分16万,参与人。

9. 国家自然科学基金青年科学基金项目《MicroRNA毒理基因组学:雌激素在小鼠体内标准图谱的研究》,2011.1-2013.12,21007030, 20万,项目负责人。

10. 教育部留学回国启动基金,《MicroRNA毒理基因组学标准图谱的研究》,2012.1-2012.12,5万,项目负责人。

11. 日本松下公司合作项目,《碱性加氢饮用水胃保护功能研究》,2012.3-2012.12,30万,项目负责人。

奖励与荣誉

2017年,JSWE-IDEA Water Environment International Exchange Award.

2016年,中国环境科学学会第十一届“优秀环境科技工作者奖”

2015年,宝钢优秀教师奖

2014年,环保部“国家环境保护专业技术青年拔尖人才”称号

2010年,中国环境科学学会第七届“青年科技奖”

2002年,教育部提名国家科学技术一等奖,第三完成人

学术成果

部分论文:

[1] Xu B, Li K, Qiao J, Liungai Z, Chen C*, Lu Y*. UV photoconversion of environmental oestrogen diethylstilbestrol and its persistence in surface water under sunlight. Water Research, 2017, 127:77-85.

[2] Li GQ; Wang WL; Huo ZY; Lu Y*; Hu HY*. Comparison of UV-LED and low pressure UV for water disinfection: photoreactivation and dark repair of Escherichia coli. Water Research, 2017, 126:134-143.

[3] Lv XT, Zhang X, Du Ye, Wu QY*, Lu Y*, Hu HY. Solar light irradiation significantly reduced cytotoxicity and disinfection byproducts in chlorinated reclaimed water. Water Research, 2017, 126:162-169.

[4] Li GQ, Yu T, Wu QY, Lu Y*, Hu HY*. Development of an ATP luminescence-based method for assimilable organic carbon determination in reclaimed water. Water Research, 2017, 123:345-352.

[5] Liu L, Zhou X*, Lu Y*, Shan D, Xu B, He M, Shi H, Qian Y. Facile screening of potential xenoestrogens by an estrogen receptor-based reusable optical biosensor. Biosensors and Bioelectronics, 2017, 97:16-20.

[6] Yu T, Meng L, Zhao Q-B, Shi Ye, Hu H-Y, Lu Y*. Effects of chemical cleaning on RO membrane inorganic, organic and microbial foulant removal in a full-scale plant for municipal wastewater reclamation. Water Research, 2017, 113:1-10.

[7] Xue J, Zhang J, Xu B, Xie J, Wu W, Lu Y*. Endotoxins: the critical risk factor in reclaimed water via inhalation exposure. Environmental Science & Technology, 2016, 50:11957-11964.

[8] Duan R, Lu Y*, Hou L, Du L, Sun L, Tang X. The U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen. Frontiers of Environmental Science & Engineering, 2016, 10(6):11.

[9] Li M, Xu B, Liungai Z, Hu H-Y, Qiao J*, Lu Y*. The removal of estrogenic activity with UV/chlorine technology and identification of novel estrogenic disinfection by-products. Journal of Hazardous Materials, 2016, 307:119-126..

[10] Yu T, Li GQ, Lin WQ, Hu H-Y, Lu Y*. Coagulation increased the growth potential of various species bacteria of the effluent of a MBR for the treatment of domestic wastewater. Environmental Science and Pollution Research, 2017, 24(6):5126-5133.

[11] Zhang J, Xue J, Xu B, Xie J, Qiao J*, Lu Y*. Inhibition of Lipopolysaccharide Induced Acute Inflammation in Lung by Chlorination. Journal of Hazardous Materials, 2016, 303:131-136.

[12] Yang Y, Lu Y*, Wu QY, Hu H-Y*, Chen YH, Liu WL. Evidence of ATP assay as an appropriate alternative of MTT assay for cytotoxicity of secondary effluents from WWTPs. Ecotoxicology and Environmental Safety, 2015, 122:490-496.

[13] Xue J, Shang G, Tanaka Y, Saihara Y, Hou L, Velasquez N, Liu W, Lu Y*. Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water, BMC Complementary and Alternative Medicine, 2014, 14:81.

[14] Shang G, Xue J, Li M, Hu HY, Lu Y*. Isolation and identification of novel estrogenic chlorination by-products of diethylstilbestrol by recombinant estrogen receptor α immobilized affinity chromatography. Chemosphere, 2014, 104:251-257.

[15] Hou LY, Lu Y*, Li Y, Li L. MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus. Frontiers of Environmental Science and Engineering, 2014, 8(1):99-105.

[16] Xue JL, Lu Y*, Velasquez N, Yu RZ, Hu HY, Liu ZT, Meng W. Introduction of risk size in the determination of uncertainty factor UFL in risk assessment. Environmental Research Letters, 2012, 7(3):034036.

[17] Xu, X; Rock, JR; Lu, Y; Futtner, C; Schwab, B; Guinney, J; Hogan, BLM; Onaitis, MW*. Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma. PNAS, 2012, 109(13): 4910-4915.

[18] Lu Y*, Hou LY,Hu HY, Li L. Progress in toxicogenomics. Ecology and Environmental Sciences, 2010, 19(9):2232-2239.

[19] Lu Y, Futtner C, Rock JR, Xu X, Whitworth W, Hogan BLM, Onaitis MW*. Evidence That SOX2 Overexpression Is Oncogenic in the Lung. Plos One 2010;5(6).

[20] Rock JR, Onaitis MW, Rawlins EL, Lu Y, Clark CP, Xue Y, Randell SH, Hogan BLM*. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proceedings of the National Academy of Sciences of the United States of America 2009;106:12771-12775.

[21] Erhunmwunsee L, Lu Y, Luo XY, Harpole DH, Hogan BLM, Onaitis MW*. Basal cells in lung cancer. Journal of the American College of Surgeons 2008;207:S30-S30.

[22] Lu Y, Thomson JM, Wong HYF, Hammond SM, Hogan BLM*. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Developmental Biology 2007;310:442-453.

专利:

陆韻,商国栋,李曼,《分离检测环境中雌激素类内分泌干扰物的方法》,申请号201310677352.6。